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Viral infection
Viral infections can also cause random bruising on legs that is unexplained. Some viral infections can cause a condition called thrombocytopenia that affects blood clotting.
According to Dr. Neha Pathak on WebMD, some common viral infections that can cause unexplained bruising are chickenpox, mumps, and rubella. Other medical conditions like HIV, aplastic anemia, or leukemia can also affect blood platelets making it more difficult for blood to clot and lead to unexplained bruising.
Autoimmune disease
Various autoimmune diseases can be a reason why you are bruising easily and can’t find the reason for it. Autoimmune disorders occur when the body produces antibodies that attack its own tissues rather than fight infections.
Some autoimmune diseases that cause unexplained random bruising are:
- Lupus. The American Academy of Family Physicians says that easy bruising and excessive bleeding can be caused by lupus.
- Rheumatoid arthritis. Apart from causing bruising in various areas of your body, the journal Annals of Rheumatic Diseases says that very often medications used to treat rheumatoid arthritis cause random bruising.
- Vasculitis. Vasculitis is inflammation of the blood vessels and one of its symptoms is bruising. The National Heart, Lung, and Blood Institute says that vasculitis can cause skin changes like purple or red spots, splotches, and bruises.
Other Causes of Unexplained Bruising
There are some serious advanced medical conditions that can also cause unexplained bruising on your body. Usually, these diseases are accompanied by other symptoms and random bruising occurs in the later stages of the disease.
Liver disease
Serious liver disease can cause easy bruising because the liver can’t produce enough blood clotting factors.
Dr. Dennis Lee on MedicineNet says that along with random bruises, liver disease can turn the skin yellow and cause all over body itching. Liver disease may also make legs swell and cause intestinal bleeding.
